
LRS 008564/10 | |
Name | Migrenium |
Dosage form | Tablets |
Nosological classification | N02BE71 Paracetamol in combination with psycholeptics |
INN | Caffeine + paracetamol |
Active agent | Active substances: paracetamol 0.500 g, caffeine 0.065 g. Excipients: potato starch, microcrystalline cellulose, croscarmellose sodium, hyprolose (oxypropyl cellulose), colloidal silicon dioxide, magnesium stearate, copovidone, talc, titanium dioxide, silicone emulsion (50% solution) |
It is suitable for getting rid of headaches, migraines, back pain, toothache, rheumatic and menstrual pain, relieving symptoms of cold, flu and sore throat.
The two components enhance each other's effect, providing a 40% more pronounced analgesic effect.*
Migrenium affects the centers of pain, tones the vessels and enhances blood circulation. The drug suppresses pain, eliminates drowsiness, feeling of tiredness, and increases performance.
Safe for use in adults and children aged 12+.
Indications:
In pain syndrome (mild to moderate):
headache;
migraine;
muscle pain;
neuralgia;
menstrual pain;
toothache;
febrile syndrome, including cold, ARVI and influenza.
How to use:
By mouth, adults and children 12+ years old – 1-2 tablets 4 times a day with an interval of at least 4 hours.
* compared to paracetamol alone.
Derry CJ, Derry S, Moore RA. Caffeine as an analgesic adjuvant for acute pain in adults. Cochrane Database Syst Rev. 2014 Dec 11;2014(12):CD009281. doi: 10.1002/14651858.CD009281.pub3. PMID: 25502052; PMCID: PMC6485702.
Kuntz D, Brossel R. Action antalgique et tolérance clinique de l'association paracétamol 500 mg-caféine 50 mg versus paracétamol 400 mg-dextropropoxyphène 30 mg dans les rachialgies [Analgesic effect and clinical tolerability of the combination of paracetamol 500 mg and caffeine 50 mg versus paracetamol 400 mg and dextropropoxyphene 30 mg in back pain]. Presse Med. 1996 Sep 7;25(25):1171–4. French. PMID: 8949620.